Autologous Plasma Eye Drops: What Are They? Health Dry Eye Autologous plasma eye drops are a treatment for severe dry eye disease where conservative treatment is failing to work. Typical treatment for dry eye disease will usually start off with using artificial tears several times a day and some patients will require gels and ointments to be used mainly during the night but sometimes also during the day. Patients with a more severe dry eye disease may need to use prescribed medication such as short-term use of steroids or immunosuppressant medication such as cyclosporine eye drops/ointment. These types of drops work by decreasing inflammation and increasing tear production. Other Dry Eye Therapies Along with the above topical treatments, the use of other therapies can be used to help the symptoms for dry eye disease such as punctal plugs; which are inserted into the tear ducts to stop tears from draining away too fast, heated eye masks and eye lid massages; to h...